Differential transcriptional modulation of duplicated fatty acid-binding protein genes by dietary fatty acids in zebrafish (Danio rerio): evidence for subfunctionalization and neofunctionalization of duplicated genes
نویسندگان
چکیده
Differential transcriptional modulation of duplicated fatty acid-binding protein genes by dietary fatty acids in zebrafish (Danio rerio): evidence for subfunctionalization and neofunctionalization of duplicated genes BMC Evolutionary Biology 2009, 9:219 doi:10.1186/1471-2148-9-219 Santhosh Karanth ([email protected]) Santosh P Lall ([email protected]) Eileen M Denovan-Wright ([email protected]) Jonathan M Wright ([email protected])
منابع مشابه
Effects of feed restriction and dietary fat type on mRNA expression of liver fatty acid-binding protein (L-FABP) in broilers
Background: Liver fatty acid-binding protein (L-FABP) is the main cytosolic binding site for long chain fatty acids in hepatocytes. FABPs enhance the uptake of fatty acids into the cell by increasing their concentration due to decreasing concentration of unbound fatty acids inside the cell. Objectives: The aim of this study was to evaluate the effects of dietary unsaturated to saturated fatty a...
متن کاملپاسخ متفاوت سلولهای قلبی به اسیدهای چرب اشباع و غیر اشباع
Introduction & Objective: The link between dietary fat and coronary heart disease has attracted much attention since the effect of long?chain fatty acids (LCFA) on gene transcription has been established, which in part, these effects can be explained by the regulation of gene transcription. In this study, the P19CL6 cardiac cell?line was targeted for the investigation of (i) the effects of long...
متن کاملDivergence of the Dof gene families in poplar, Arabidopsis, and rice suggests multiple modes of gene evolution after duplication.
It is widely accepted that gene duplication is a primary source of genetic novelty. However, the evolutionary fate of duplicated genes remains largely unresolved. The classical Ohno's Duplication-Retention-Non/Neofunctionalization theory, and the recently proposed alternatives such as subfunctionalization or duplication-degeneration-complementation, and subneofunctionalization, each can explain...
متن کاملThe CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.
Theories predict that the long-term survival of duplicated genes requires their functional diversification, which can be accomplished by either subfunctionalization (the partitioning of ancestral functions among duplicates) or neofunctionalization (the acquisition of novel function). Here, we characterize the CDY-related mammalian gene family, focusing on three aspects of its evolution: gene co...
متن کاملCALL FOR PAPERS Comparative Genomics Conserved expression of alternative splicing variants of peroxisomal acyl-CoA oxidase 1 in vertebrates and developmental and nutritional regulation in fish
Morais S, Knoll-Gellida A, André M, Barthe C, Babin PJ. Conserved expression of alternative splicing variants of peroxisomal acylCoA oxidase 1 in vertebrates and developmental and nutritional regulation in fish. Physiol Genomics 28: 239–252, 2007. First published November 7, 2006; doi:10.1152/physiolgenomics.00136.2006.—The acyl-coenzyme A oxidase 1 (ACOX1) catalyzes the first, rate-limiting st...
متن کامل